What we do
What it is and how this project will contribute
The Genome of Europe (GoE) project aims to establish a unique pan-European reference database comprising a minimum of 100,000 genomes representative of European citizens in alignment with the 1+ Million Genomes initiative.
Key objectives include:
- Implementing a pan-European community of practice that will generate the reference genome through integration of existing genome datasets and de novo sequencing from diverse national populations,
- Defining the ethical, legal and societal conditions for generating the reference genome,
- Ensuring data security,
- Embedding GoE data within the Digital Europe Programme-funded Genomic Data Infrastructure (GDI).
The value and usability of the GoE will be assessed through use cases focusing on genetic diversity, establishing multi-ancestry imputation services, and recalibrating genetic risk profiles.
- Contribute 100 000 samples to 1+Million genomes
- Benchmark & guide ethical and legal issues
- Provide an accessible and secure genetic dataset
- Demonstrate scientific and clinical value through pilots and use-cases
- Engage with stakeholders through communication and dissemination
- Synergize with multiple EU Data and Health initiatives
Beyond the project, GoE will be highly relevant for genetic-phenotypic discoveries, helping national genome programs, and integration of genomics into the European Health Data Space (EHDS). The GoE project prioritizes public engagement, transparency, and adaptability for future extensions, ensuring responsible and sustainable genomic advancements. Integration with other European initiatives enhances its potential impact for personalized medicine, and aligns with broader scientific and healthcare goals including the European competitiveness in genomic research and innovation.